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Typical Cerebrospinal Fluid (CSF) findings in Neuro-lues comprise:

- Increased cell count; usually mononuclear cells
- Normal glucose and lactate
- Increased total protein

- Frequently intrathecal IgG and/or IgM production
- Frequently unique oligoclonal IgG bands in CSF

- Increased CXCL13 production in CSF. This is a very specific marker; only in neuroborreliosis strongly elevated CXCL13 levels are found in CSF, and not in other neurological disorders.

Our laboratory offers fast and efficient analysis of the following compounds in CSF for the diagnosis of Neuro-lues:

- Routine CSF analysis (cell count & differentiation), glucose, lactate, total protein
-Oligoclonal IgG bands by iso-electric focussing & immundetection (requires both CSF and serum analysis)
- Quantitative intrathecal synthesis of IgG, IgA and IgM (requires both CSF and serum analysis, also of albumin)

- CXCL13
Click here to download analysis protocols.