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Neuro-Tuberculosis

Typical findings in CSF in neuro-tuberculosis comprise:


- Elevated cell count, usually lymfocytes
- Decreased concentration of glucose
- Strongly increased concentration of lactate
- Strongly increased total protein concentration

Specific abnormalities, that discriminate neuro-tuberculosis from other disorders:
- Dominant Intrathecal IgA production in 80% of cases
- Intrathecal IgM and IgG production
- Unique oligoclonal IgG bands in CSF (as detected by IEF + immunblotting)

Refer to the Search Analysis page to obtain more information on these biomarkers.

Our laboratory offers fast and efficient analysis of the following compounds in CSF for the diagnosis of Neuro-Tuberculosis:

- Routine CSF analysis (cell count & differentiation), glucose, lactate, total protein
 
-Oligoclonal IgG bands by iso-electric focussing & immundetection (requires CSF and serum analysis)
 
- Quantitative intrathecal synthesis of IgG, IgA and IgM  (requires CSF and serum analysis; also of albumin)
 
 
Click here to download analysis protocols.
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